Rafting in the membrane. A lesson learnt from lymphoproliferative disorders.
نویسنده
چکیده
Lipid rafts are chemically distinct compartments of the plasma membrane. Their integrity is a prerequisite for vital cellular functions particularly for signalling and trafficking. Their perturbation is associated with development of a broad spectrum of diseases. Lipid rafts are also important for therapeutic effects of some drugs. Moreover, some of the raft associated molecules are useful immunohistochemical markers in routine histopathology.
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ورودعنوان ژورنال:
- Ceskoslovenska patologie
دوره 44 4 شماره
صفحات -
تاریخ انتشار 2008